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What medications interact with fluoxetine?

The major fluoxetine-drug interactions involve the amino acids L-dopa and L-tryptophan, anorexiants, anticonvulsants, antidepressants, anxiolytics, calcium channel blockers, cyproheptadine, lithium salts, and drugs of abuse.

What drugs interact with SSRIs?

Introduction

SSRI Interacting Drug
Paroxetine Antiepileptics, carbamazepine and phenytoin
All NSAIDs including aspirin
All Monoamaine oxidase inhibitors (MAOIs), including moclobemide
Fluoxetine & paroxetine (possibly citalopram) Clozapine, haloperidol and risperidone

What SSRIs to avoid?

Some of the medications that can interact with some SSRIs include: non-steroidal anti-inflammatory drugs (NSAIDs) – a common type of painkiller that includes ibuprofen, diclofenac or naproxen. antiplatelets – a type of medication used to prevent blood clots, such as low-dose aspirin and clopidogrel.

Which SSRI has least drug interactions?

Citalopram and sertraline, which have relatively little effect on the P450 system and wash out of the body relatively quickly, are the least likely of the SSRIs to interact with a replacement drug.

Which is the safest antidepressant?

The investigators recommend sertraline as the best choice for an initial antidepressant because it is available in generic form and is therefore lower in cost. They further recommend that sertraline, instead of fluoxetine or placebo, be the new standard against which other antidepressants are compared.

Is it bad to take antidepressants long-term?

Long-term antidepressant users are risking permanent damage to their bodies, according to leading medical experts. Dr Tony Kendrick, a professor of primary care at the University of Southampton, says more urgent action needs to be taken to encourage and support long-term users to come off the medication.

What are the side effects of long-term use of antidepressants?

Long-Term Effects of Antidepressants

  • Sexual problems (72%), including the inability to reach orgasm (65%)
  • Weight gain (65%)
  • Feeling emotionally numb (65%)
  • Not feeling like themselves (54%)
  • Reduced positive feelings (46%)
  • Feeling as if they’re addicted (43%)
  • Caring less about other people (36%)
  • Feeling suicidal (36%)

Do antidepressants cause dementia?

New evidence shows some anti-depressants can raise dementia risk. Certain antidepressants and bladder medications are linked to increased risk of dementia, according to new University of East Anglia research funded by Alzheimer’s Society and published today in the British Medical Journal.

Do antidepressants affect decision making?

Interestingly, antidepressants don’t appear to improve decision making even when they improve mood. Depression affects your decision making in several ways. When we say depression leads to poorer decision, it means that the decisions lead to outcomes that have less positive impact on your life over the long run.

How does mental illness affect decision making?

For those living with mental health conditions or facing mental health challenges such as anxiety, decision-making can become more challenging. Studies have shown that anxiety disrupts the decision-making regions of the prefrontal cortex. It is essential to reduce anxiety in order to improve one’s decision-making.

How long does it take to feel normal after stopping antidepressants?

Withdrawal symptoms usually come on within 5 days of stopping the medicine and generally last for up to 6 weeks. Some people have severe withdrawal symptoms that last for several months or more. See your doctor if you get severe withdrawal symptoms after you stop taking antidepressants.

Can antidepressants cause lack of empathy?

Novel insights show that antidepressant treatment can lead to impaired empathy regarding perception of pain, and not just the state of depression itself. Depression is a disorder that often comes along with strong impairments of social functioning.

Does emotional blunting go away after antidepressant?

But you don’t have to lose your ability to feel joy just to get rid of the pain: Emotional blunting is best resolved by switching to a different class of antidepressants, adding a second medication, or talking with a therapist, Combs says.

Is emotional blunting permanent?

Despite how it may feel, emotional numbness is not permanent. Treatment is available to provide both immediate relief and long-term remission.