General Overview. Gene therapy holds great promise for treating cancer, inherited disorders, and other diseases. Gene therapy uses carriers called ‘vectors’ to deliver genes to tissues where they are needed.

Clinical trials of gene therapy in people have shown some success in treating certain diseases, such as: Severe combined immune deficiency. Hemophilia. Blindness caused by retinitis pigmentosa.

These agents are extremely good at inserting their genes into the DNA of host cells. More than 30 patients have been treated for SCID, and more than 90 percent of those children have been cured of their disorder—an improvement over the 50 percent chance of recovery offered by bone marrow transplants.

FDA Efforts Between preclinical study and clinical trials, the process can take many years to conclude. Clinical trials alone sometimes can take eight years or more.

Zolgensma is the most expensive medical drug in the world right now and has been approved by the United Kingdom’s National Health Service (NHS). To use 1 dose of Zoldensma will cost Rs. 18 crore(£1.79 million) of your hard-earned money.

Hyd boy gets world’s most expensive medicine as parents mobilise ₹16 crore. Three-year old Ayaansh from Hyderabad, suffering from a rare disease Spinal Muscular Atrophy (SMA), has been administered the world’s costliest medicine Zolgensma.

What are the treatment options for spinal muscular atrophy? The recent discovery of the genetic cause of SMA has led to the development of two new treatment options — a gene replacement therapy called Zolgensma (previously AVXS-101) and a drug called nusinersen (brand name Spinraza). Both have shown promising results.

There’s currently no cure for SMA, but the Food and Drug Administration (FDA) has recently approved several new treatments for both type 1 and type 2 SMA, including innovative gene therapies, with many more potential treatments on the horizon.

Infants with type 1 SMA usually die before their second birthday. Children with type 2 or type 3 SMA may live full lives depending on the severity of symptoms. People who develop SMA during adulthood (type 4) often remain active and enjoy a normal life expectancy.

Zolgensma which has a reported list price of £1.79 million( ₹18 crore) per dose is labelled the most expensive drug in the world. Zolgensma was approved by the NHS England on Monday to treat babies with a rare fatal genetic disorder.

Scopolamine – also known as Devil’s Breath – has a reputation for being an extremely dangerous drug. In 2012, a Vice documentary dubbed it the “world’s scariest drug”.

Coke drinkers are likely to see prices for their favorite drinks rise this year. The increase in price is due in part to President Donald Trump’s steel and aluminum tariffs. The company has already raised its prices in the US and that price increases for consumers are being left to bottlers and retailers.

Finance. Pepsi’s stock is nearly 20% less expensive than Coca-Cola’s in terms of price to free cash flow….Valuation.

Zolgensma, a drug that treats spinal muscular atrophy, is the most expensive drug in the U.S. with an estimated annual cost of $2,125,000, according to research released March 8 by GoodRx.

Some people prefer it in a can, others prefer a glass or plastic bottle. While soda companies claim that the recipe doesn’t change, there are a few factors that might affect the way you taste a soda depending on the container. Cans are significantly better than bottles.

Why Mexican Coke Is Better In the end, it really does come down to taste. Mexican Coke uses natural cane sugar, and even if it has the same number of calories and really isn’t healthier than high fructose corn syrup — it just tastes better! Plus, it comes in those perfect small glass bottles.

For example, aluminum cans are lined with a polymer that can absorb small amounts of flavor and plastic bottles may transfer acetaldehyde that can alter the way a drink tastes. Glass is a more inert material than either aluminum or plastic, so it’s less likely to affect the flavor of your drink.

Cans Keep Beer Fresher Because beer cans limit exposure to both light and oxygen, they keep the beer inside fresh and flavorful for longer. However, aluminum cans prevent all light from reaching the beer inside. Additionally, cans create a better airtight seal than beer bottles.

Americans continue to drink canned beverages and eat food from cans lined with BPA. BPA is found in the linings of most canned foods and most aluminum cans, including Coca-Cola products. Now, a new study suggests that even small doses of BPA can significantly increase blood pressure in adults.

Beer was stored in clear glass and when left in the sun for too long, it started to smell “skunky” – like a skunk, literally. This was because the clear glass allowed UV rays to penetrate the beer and alter the flavour. The solution was turning bottles brown, a darker colour which would block out the rays.

Ultimately, the lifecycle analysis considers glass bottles more environmentally friendly due to their lower greenhouse gas emissions that aluminum cans, which are estimated to result in 1.88 times more emissions.

Glass that is collected and sorted through curbside programs is “highly contaminated,” making the materials “useless.” “Glass recycling companies do not usually want this glass,” Prischak says. “In addition, broken glass can stick to paper and cardboard, contaminating those materials.

BENGALURU: Three girls suffering from the rare disease, Spinal Muscular Atrophy, were administered the expensive gene therapy, Zolgensma, for free at Bangalore Baptist Hospital on Thursday. Each vial of the one-time injection costs Rs 16 crore and is capable of changing the genetic code in the body.

In 2020, Myalept remains the most expensive pharmacy drug in the U.S. at a whopping $71,306 per month. The drug, which treats complications caused by leptin deficiency in people who have lipodystrophy, has had numerous owners over the years, and its latest, Amryt, raised its price by 9.9% in January.

The world’s most expensive work of art sold at auction is a 500-year-old painting of Christ believed to have been painted by Leonardo da Vinci. The painting, which is known as Salvator Mundi (Saviour of the World), sold at Christie’s in New York for a record $450m (£341m) in 2017.

The Most Expensive Gemstone in the World: The Blue Diamond

• Are worth $3.93 million per carat.
• Are rare to find in a flawless sample.
• Cause a huge stir in the jewelry industry when one goes to auction.

Painite

red diamond

De Beers

Russia

China is the number one producer of gold in the world. The USGS estimates that China mined 455 metric tons of gold in 2016. Since gold began to be mined in the 1970s, gold production in China has rapidly increased. China finally overtook South Africa in 2007 as the world’s top gold producer.

Which Countries are the Best for Buying Pure Gold?

• The Emirate of Dubai, UAE. Whenever you talk about Dubai, the thought of purchasing gold definitely comes in your head.
• Hong Kong, China.
• Cochin, India.
• Bangkok, Thailand.
• Zurich, Switzerland.