This video shows how to fix error 1603 while installing or uninstalling an application like skype Microsoft Fix It a free application which automatically fixes all registry errors including error 1603.
Steps
1- Install Microsoft Fix it from the link
http://support.microsoft.com/mats/Program_Install_and_Uninstall/
2- Run the programme and it automatically fixes the problem
3- Install or Uninstall whatever programmes you like

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